Golden Globes, USA 2006
| Nominee Golden Globe | Best Television Series – Drama |
| Best Performance by an Actor in a Television Series – Drama Wentworth Miller |
| Nominee Saturn Award | Best Network Television Series |
| Best Actor on Television Wentworth Miller |
ALMA Awards 2009
| Nominee ALMA Award | Actor in Television – Drama Amaury Nolasco |
ALMA Awards 2008
| Nominee ALMA Award | Outstanding Supporting Actor in a Drama Television Series Amaury Nolasco |
ALMA Awards 2006
| Winner ALMA Award | Outstanding Director of a Television Drama or Comedy Jesus Salvador |
| Nominee ALMA Award | Outstanding Supporting Actor in a Television Series Amaury Nolasco |
American Cinema Editors, USA 2006
| Nominee Eddie | Best Edited One-Hour Series for Commercial Television Mark HeΩ Episode: “Bekstvo iz Zatvora (2005)” |
Australian Film Institute 2007
| Winner AFI International Award | Best Actor Dominic Purcell |
Gran Premio Internazionale del Doppiaggio 2009
| Nominee TV Award | Best TV Series For Season 3. |
Online Film & Television Association 2006
| Nominee OFTA Television Award | Best Drama Series |
| Best Direction in a Drama Series |
People’s Choice Awards, USA 2006
| Winner People’s Choice Award | Favorite New Television Drama |
Satellite Awards 2006
| Nominee Satellite Aw-ard | Best Actor in a Supporting Role in a Series, Mini-Series or Motion Picture Mad-e for Television Robert Knepper |
Teen Choice Awards 2007
| Nominee Teen Choice Award | Choice TV Actor: Action Wentworth Miller |
Teen Choice Awards 2008
| Nominee Teen Choice Award | Choice TV Show: Action Adventure |
| Choice TV Actor: Action Adventure Wentworth Miller |
Teen Choice Awards 2006
| Nominee Teen Choice Award | TV – Choice Actor Wentworth Miller |
| TV – Choice Breakout Star Wentworth Miller | |
| TV – Choice Sidekick Amaury Nolasco | |
| TV – Choice Breakout Show |
Prison Break 